While it is increasingly outlined the link between gut microbiota and several systemic and gastrointestinal diseases, to date the role of the oral microbiota is not well clarified.

Different factors like diet, smoke, alcohol, and use of probiotics have an active role in the development and modification of the oral microbiota. The relation between oral microbiota and oral diseases was better studied in the past, but during the last years, a deeper link between systemic disease and oral microbiota was discovered.

This review aims to summarize the results of the most relevant studies published on this topic between April 2018 and March 2019.